Advancing Treatment Strategies in Metastatic Castration-Resistant Prostate Cancer: The Urologists Role

Release Date: August 3, 2015
Last Reviewed: July 29, 2015
Expiration Date: August 3, 2016
Time to Complete Activity: 1.0 hour

*This activity expired for credit on August 3, 2016 and is no longer available for credit

This activity is provided by the University of Cincinnati. Global Education Group and Paradigm Medical Communications, LLC are the educational partners.

Faculty
Neal D. Shore, MD (Chair)

Medical Director
Carolina Urologic Research Center
Atlantic Urology Clinics
Myrtle Beach, SC

E. David Crawford, MD
Professor of Surgery/Urology/Radiation Oncology
E. David Crawford Endowed Chair in Urologic Oncology
Head Urologic Oncology
University of Colorado, Denver
Aurora, CO

Celestia S. Higano, MD, FACP
Professor, Department of Medicine
Division of Oncology
Professor, Department of Urology
University of Washington
Seattle, WA

Oliver Sartor, MD
LaBorde Professor for Cancer Research
Medical Director Tulane Cancer Center
Departments of Medicine and Urology
Tulane Medical School
New Orleans, LA

Target Audience
This activity has been designed to meet the educational needs of physicians specializing in urology, uro-oncology, medical oncology, and radiation oncology. This activity will also be of benefit to other healthcare professionals interested in the management of patients with metastatic castration-resistant prostate cancer (mCRPC).

Learning Objectives
Upon proper completion of this activity, participants should be better able to:

  • Describe comprehensive monitoring parameters that may indicate efficacy of therapy or help guide management decisions for the treatment of mCRPC.
  • Recognize differences among agents for mCRPC in order to make evidence-based, individualized treatment decisions for patients with mCRPC.
  • Evaluate successful multidisciplinary models of care for the management of patients with mCRPC.

Agenda

  • Introduction to Treatment of Castration-resistant Prostate Cancer (CRPC)
  • Newer Therapies Overview
  • What the Guidelines Do (and Don’t) Tell Us
    • NCCN, ASCO, AUA
    • Guideline Limitations and Decisions in the Clinic
  • The Urologist’s Care: A Case-Based Journey Through the Progression of CRPC
  • Conclusion

Accreditation Statement
The University of Cincinnati, Global Education Group, and Paradigm Medical Communications, LLC are each accredited by the ACCME to provide continuing medical education for physicians, and have collaborated to design and execute this enduring activity.

For accreditation purposes, the University of Cincinnati is responsible for certification and documentation of attendance for this activity.

The University of Cincinnati is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation Statement
The University of Cincinnati designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For information about the accreditation of this program, please contact the University of Cincinnati at (513) 558-3197 or forneyba@uc.edu.

Disclosure of Commercial Support
This activity is supported by educational grants from Astellas and sanofi-aventis U.S. Inc.

Instructions for Participation
To receive a CME certificate of participation, you should:

  • Follow instructions to register or log in with your professional information and complete the pre-activity assessment
  • View the online activity in its entirety.
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest.

A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.

For questions regarding CME credit, contact the Paradigm CME Department at (845) 398-5949.

There is no fee required for participation in this activity.

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Disclosures
In accordance with Accreditation Council for Continuing Medical Education requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below.

Faculty
Neal D. Shore, MD (Chair)

Advisory Board: Astellas Pharma US, Inc; Bayer; Dendreon Corporation; Ferring Pharmaceuticals; Janssen Pharmaceuticals, Inc; Millennium Pharmaceuticals, Inc; Sanofi
Retained Consultant: Astellas Pharma US, Inc; Bayer; Dendreon Corporation; Ferring Pharmaceuticals; Janssen Pharmaceuticals, Inc; Millennium Pharmaceuticals, Inc; Sanofi


E. David Crawford, MD
Advisory Board: Ferring Pharmaceuticals
Grant Recipient: NIH
Retained Consultant: Ferring Pharmaceuticals
Speakers Bureau: Bayer


Celestia S. Higano, MD, FACP
Advisory Board: Bayer HealthCare; Dendreon Corporation; Genentech, Inc; Orion Corporation
Board Member (Spouse): CTI BioPharma Corp
Employee (Spouse): CTI BioPharma Corp
Grant Recipient (Institutional Support): Algeta ASA; Aragon Pharmaceuticals; Bayer HealthCare; Dendreon Corporation; Emergent BioSolutions Inc; Medivation, Inc; Millennium Pharmaceuticals, Inc; Sanofi US
Retained Consultant: Astellas Pharma US, Inc; Millennium Pharmaceuticals, Inc; Pfizer Inc
Stockholder (Spouse): CTI BioPharma Corp


Oliver Sartor, MD
Grant/Research Support (Clinical Trials): Bayer; Janssen Pharmaceuticals, Inc; Sanofi
Retained Consultant: Astellas Pharma US, Inc; Bayer; BN ImmunoTherapeutics Inc; Janssen Pharmaceuticals, Inc; Medivation, Inc; OncoGenex Pharmaceuticals Inc; Sanofi


Planning Committee Member
Barb Forney, CME compliance: no relevant relationships

Rick Ricer, MD, University of Cincinnati College of Medicine: no relevant relationships

Amanda Glazer, PhD, Kelly Enders, and Laura Gilsdorf, independent clinical reviewers from Global Education Group for this program: no financial relationships to disclose

Paradigm Medical Communications, LLC staff members: no financial relationships to disclose

Off-Label Disclosure Statement
Faculty members are required to inform the audience when they are discussing off-label, unapproved uses of devices and drugs.  Physicians should consult full prescribing information before using any product mentioned during this educational activity.

Learner Assurance Statement
The University of Cincinnati is committed to resolving all conflict of interest issues that could arise as a result of prospective faculty members’ significant relationships with drug or device manufacturer(s).  The University of Cincinnati is committed to retaining only those speakers with financial interests that can be reconciled with the goals and educational integrity of the CME activity.

Disclaimer Statement
The opinions expressed during the enduring activity are those of the faculty and do not necessarily represent the views of the University of Cincinnati, Global Education Group, or Paradigm Medical Communications, LLC. The information is presented for the purpose of advancing the attendees’ professional development.

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