The Evolving Role of Oral Anticoagulation in Internal Medicine: NVAF, DVT, and PE Best Practices
Release Date: July 6, 2016
Last Reviewed: June 10, 2016
Expiration Date: July 6, 2017
Time to Complete Activity:  1.0 hour
*This activity expired for credit on July 6, 2017 and is no longer available for credit
 Tracy Minichiello, MD (Chair)
 Professor of Medicine
 University of California, San Francisco
 Chief, Anticoagulation and Thrombosis Services
 San Francisco VA Medical Center
 San Francisco, CA

 John Fanikos, RPh, MBA
 Executive Director of Pharmacy
 Brigham and Women’s Hospital
 Boston, MA

 Robert P. Giugliano, MD, SM, FACC, FAHA
 Senior Investigator, TIMI Study Group
 Associate Physician, Cardiovascular Division
 Brigham and Women’s Hospital
 Associate Professor of Medicine
 Harvard Medical School
 Boston, MA

 Charles V. Pollack, Jr., MA, MD, FACEP, FAAEM, FAHA, FESC, FCPP
 Associate Provost for Innovation in Education
 Thomas Jefferson University
 Director, Jefferson Institute of Emerging Health Professions
 Associate Dean for CME and Strategic Partner Alliances
 Thomas Jefferson University
 Professor and Senior Advisor for Interdisciplinary Research and Clinical Trials
 Department of Emergency Medicine
 Sidney Kimmel Medical College of Thomas Jefferson University
 Philadelphia, PA

This activity is provided by Paradigm Medical Communications, LLC.  
Target Audience
This activity has been designed to address the educational needs of physicians, nurse practitioners, and physician assistants specializing in internal medicine. It may also be of benefit to other healthcare professionals (HCPs) who are interested in the management of thrombosis with direct oral anticoagulants.
Learning Objectives
Upon proper completion of this activity, participants should be better able to:
  • Apply guideline-recommended risk assessment tools to evaluate risks of stroke and/or bleeding among patients with nonvalvular atrial fibrillation and/or venous thromboembolism.
  • Identify the various indications for, and contraindications to, the use of direct oral anticoagulants.
  • Choose evidence-based, individualized direct oral anticoagulant therapy based on individual patient characteristics.
Introduction and Overview
Chapter 1: Selecting and Managing Direct Oral Anticoagulant Therapy in Patients with Nonvalvular Atrial Fibrillation
Chapter 2: Direct Oral Anticoagulant Therapy in Patients with Venous Thromboembolism
Chapter 3: Reversal Strategies for Direct Oral Anticoagulant Therapy
Chapter 4: Improving the Care of Patients Receiving Direct Oral Anticoagulants in Internal Medicine: Bridging the Gaps During Transitions of Care
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Paradigm Medical Communications, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physician Assistant Continuing Education
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Disclosure of Commercial Support
This activity is supported by independent educational grants from Boehringer Ingelheim Pharmaceuticals, Inc. and Daiichi Sankyo, Inc.
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  • View the online activity in its entirety.
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest.
A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.

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In accordance with Accreditation Council for Continuing Medical Education requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below.
Tracy Minichiello, MD (Chair)
No financial relationships to disclose.

John Fanikos, RPh, MBA
Retained Consultant: Baxalta, Inc; BD Rx, Inc; Boehringer Ingelheim Pharmaceuticals, Inc
Robert P. Giugliano, MD, SM, FACC, FAHA
Retained Consultant: Amarin Corp; American College of Cardiology; Amgen Inc; CVS/caremark; Daiichi Sankyo, Inc; GlaxoSmithKline; Lexicon Pharmaceuticals, Inc; Merck & Co, Inc; Portola Pharmaceuticals, Inc; Pfizer Inc; St Jude Medical; Stealth Peptides, Inc
Honoraria: Amgen Inc; Daiichi Sankyo, Inc; Merck & Co, Inc
Grant/Research Support: Amgen Inc; Merck & Co, Inc
Charles V. Pollack, Jr., MA, MD, FACEP, FAAEM, FAHA, FESC, FCPP
Retained Consultant: Boehringer Ingelheim Pharmaceuticals, Inc, Bristol-Myers Squibb Company/Pfizer Inc, Daiichi Sankyo, Inc, Janssen Pharmaceuticals, Inc
Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.

Independent peer reviewer has no financial relationships to disclose.
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