Addressing Postprandial Glucose Excursions: An Update on the Implications and New Management Strategies for Patients with Diabetes

Live Symposium Date: May 17, 2018
Release Date: August 28, 2018
Expiration Date: August 28, 2019
Time to Complete Activity:  1.75 hours

 

*This activity expired for credit on August 28, 2019 and is no longer available for credit 
 

 
Faculty
Richard E. Pratley, MD (Chair)
Director and Samuel E. Crockett Chair in Diabetes Research
Florida Hospital Diabetes Institute
Senior Investigator and Diabetes Program Lead
Translational Research Institute for Metabolism and Diabetes
Adjunct Professor, Sanford Burnham Prebys
Medical Discovery Institute
Orlando, FL
 
Bruce W. Bode, MD
Clinical Associate Professor
Division of Endocrinology, Metabolism and Lipids
Department of Medicine
Emory University
Atlanta, GA
 
Irl B. Hirsch, MD
Professor of Medicine
Diabetes Treatment and Teaching Chair
Division of Metabolism, Endocrinology and Nutrition
Department of Medicine
University of Washington
Seattle, WA
 
Guillermo E. Umpierrez, MD
Professor of Medicine
Department of Medicine
Emory University School of Medicine
Section Chief, Diabetes and Endocrinology Division
Grady Health System
Atlanta, GA
 

     This activity is provided by the American Association of Clinical Endocrinologists. 
 
      Program management provided by Paradigm Medical Communications, LLC.

Target Audience
This activity has been designed to address the educational needs of endocrinologists. It may also benefit diabetes specialists, primary care physicians, hospitalists, certified diabetes educators, PAs, nurse practitioners (NPs), pharmacists, managed care clinicians, and other clinicians who care for patients with diabetes.
 
Statement of Need
Despite demonstration of decreased cardiovascular risk with lowered postprandial glucose levels and the availability of fast-acting insulins to treat postprandial glucose excursions (PPGE), debate remains about the necessity of treating PPGE. It is critical that clinicians who manage patients with diabetes keep up to date with the latest emerging evidence for newer, ultra-fast-acting prandial insulins, as this is an evolving category. Whereas prandial insulin use primarily pertains to type 1 diabetes, a number of people with type 2 diabetes also benefit from prandial insulin. Endocrinologists and diabetes specialists need to understand how to tailor diabetes care according to individual patient backgrounds and characteristics, especially with respect to prandial insulin. They also require an understanding of the most recently updated guidelines about the appropriate use of prandial insulin therapy, and how patient factors influence selection of appropriate insulin regimens. This educational activity will address postprandial hyperglycemia and its treatment.
 
Learning Objectives
Upon proper completion of this activity, participants should be better able to:
  • Discuss the implications of postprandial hyperglycemia for patients with diabetes.
  • Describe how ultra-fast-acting insulins are used to mimic physiologic insulin for patients with diabetes.
  • Outline appropriate use of ultra-fast-acting insulins for patients with diabetes.

Table of Contents
  • Welcome and Program Overview
  • Awareness and Consequences of Glycemic Variability
  • Strategies for Managing Postprandial Glucose Excursions
  • New Approaches to Bolus Insulin Administration
  • Panel Discussion/Q&A
Physician Accreditation Statement
The American Association of Clinical Endocrinologists (AACE) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
 
The American Association of Clinical Endocrinologists (AACE) designates this enduring material for a maximum of 1.75 AMA PRA Category 1 Credit(s)™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For information about the accreditation for this program, please contact AACE CME department at CME@aace.com.

PA Continuing Education
PAs may claim a maximum of 1.75 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society.
 
Nurse Practitioner Continuing Education
The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.  Individuals are responsible for checking with the AANPCP for further guidelines.
 
Disclosure of Commercial Support
This activity is supported by an educational grant from Novo Nordisk Inc.
 
Instructions for Participation
To receive a CME certificate of participation, you should:
  • Follow instructions to register or log in with your professional information and complete the pre-activity assessment
  • View the online activity in its entirety.
  • Complete and submit the online posttest and evaluation.
A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.

For questions regarding CME credit, please contact the Paradigm CME Department at (845) 398-5949.
 
There is no fee required for participation in this activity.

Hardware/Software Requirements
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Technical Support: If you have any technical problems or playback issues email us at contactus@paradigmmc.com.
 
Declaration and Disclosure of Conflict of Interest
It is the policy of AACE to ensure balance, independence, objectivity, and scientific rigor in all of its CME activities.  Presentation content may include discussion of an unlabeled use of a commercial product or an investigational use of a product not yet approved for any purpose.  AACE requires that participating faculty disclose to the audience any product(s) and its use(s) discussed in the educational activity that are unapproved/unlabeled for the use by the FDA or still considered investigational in nature. 
 
Everyone who is in a position to control the content of an educational activity must disclose all relevant financial relationships. “Relevant financial relationships” are financial relationships in any amount occurring within the past 12 months that create a conflict of interest.  AACE requires speakers, faculty, CME Committee, and other individuals who are in a position to control the content of this educational activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity.  All identified conflicts of interest are thoroughly evaluated by AACE for fair balance, scientific objectivity of studies mentioned in the presentation, and educational materials used as basis for content, and appropriateness of patient care recommendations. 
 
The intent of this disclosure is not to prevent a speaker with commercial affiliations from presenting, but rather to provide learners with information from which they may make their own judgments.  Informed learners are the final safeguards in assuring that a CME activity is independent from commercial influence. 
 
AACE has reviewed all disclosures and resolved or managed all identified conflicts of interest for this educational activity, as applicable.
 
CME Accreditation Committee Disclosures
Myriam Allende-Vigo, MD, MBA, FACP, FACE
Advisory Board: Merck & Co., Inc.
 
Joshua I. Barzilay, MD, FACE
Stockholder: AbbVie Inc; Bristol Myers Squibb Company; Merck & Co., Inc; Pfizer Inc.; sanofi-aventis U.S. LLC; Teva Pharmaceutical Industries Ltd

Tamis Bright, MD
Salary: Southwest ENT (Spouse)
 
Philip Raskin, MD, FACE
Advisory Board: Intarcia Therapeutics
Grant/Research Support: Amylin Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals, Inc; Gan & Lee Pharmaceuticals
Retained Consultant: Reata Pharmaceuticals, Inc.
 
Nothing to Disclose:
Ricardo Correa, MD
Diane Donegan, MBChB
Kurt Kennel, MD, FACE
Phillip D.K. Lee, MD, FAAP, FACE
Jad Sfeir, MD
Jagdeesh Ullal, MD, FACE, ECNU
Rong Mei Zhang, MD
 
Program Committee Disclosures
Joseph Aloi, MD, FACP
Retained Consultant: DexCom, Inc; Medtronic, Inc
 
Pauline M. Camacho, MD
Grant/Research Support: Amgen Inc.; NPS Pharmaceuticals
Advisory Board: Amgen Inc.
 
Jay Cohen, MD
Grant/Research Support: Eli Lilly and Company; Janssen Pharmaceuticals Inc; Merck & Co., Inc; Novo Nordisk Inc.; sanofi-aventis U.S. LLC
Speakers Bureau: AbbVie Inc; AstraZeneca; Boehringer Ingelheim Pharmaceuticals, Inc; Corcept Therapeutics; Eli Lilly and Company; Endo Pharmaceuticals Inc; Janssen Pharmaceuticals Inc.; Merck & Co., Inc; Novo Nordisk Inc.; sanofi-aventis U.S. LLC
Advisory Board: Corcept Therapeutics; Endo Pharmaceuticals Inc
 
Jaime A. Davidson, MD, FACP
Retained Consultant: Aspire Bariatrics; GlaxoSmithKline
Speakers Bureau: AstraZeneca/ Bristol Meyers Squibb; Janssen Pharmaceuticals Inc.; Novo Nordisk Inc.
Advisory Board: AstraZeneca/ Bristol Meyers Squibb; Eli Lilly and Company: Merck & Co., Inc; Novo Nordisk Inc.; Valeritas
 
Vivian Fonseca, MD (Program Vice-Chair)
Grant/Research Support: Bayer HealthCare; Boehringer Ingelheim Pharmaceuticals, Inc.
 
Jeffrey R. Garber, MD, FACP
Retained Consultant: AbbVie Inc.; Kashiv Pharma, LLC; Titan Pharmaceuticals, Inc
Advisory Board: Lio Tri Dev
 
W. Timothy Garvey, MD
Grant/Research Support: AstraZeneca; Eisai Inc.; Lexicon Pharmaceuticals Inc.; Merck & Co., Inc.; Novo Nordisk Inc; Pfizer Inc.; sanofi-aventis U.S. LLC
Retained Consultant: Alexion; AstraZeneca; Eisai Inc.; Janssen Pharmaceuticals Inc; Merck & Co., Inc.; Novo Nordisk Inc; Takeda Pharmaceutical Company Ltd.
Stockholder: Bristol Myers Squibb Company; Eli Lilly and Company; ISIS; Merck & Co., Inc.; Novartis; Pfizer Inc.
 
Chris Guerin, MD, FACE, FNLA
Speaker’s Bureau: Abbott Medical Devices; Novo Nordisk Inc
Advisory Board: Novo Nordisk Inc.
Teaching: Janssen Pharmaceuticals Inc.; sanofi-aventis U.S. LLC
 
Yehuda Handelsman, MD, FACP, FNLA
Grant/Research Support: Amgen Inc.; Boehringer Ingelheim Pharmaceuticals, Inc; Gilead Sciences Inc.; GlaxoSmithKline; Intarcia Therapeutics; Lexicon Pharmaceuticals, Inc; Merck & Co., Inc; Novo Nordisk Inc.; sanofi-aventis U.S. LLC; Takeda Pharmaceutical Company Ltd.
Retained Consultant: Amarin Corporation; Amgen Inc.; Amylin Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals, Inc; Gilead Sciences Inc.; GlaxoSmithKline; Halozyme, Inc; Janssen Pharmaceuticals Inc.; Merck & Co., Inc; Novo Nordisk Inc.; sanofi-aventis U.S. LLC; Vivus Inc
Speakers Bureau: Amarin Corporation; Amylin Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals, Inc; GlaxoSmithKline; Janssen Pharmaceuticals Inc.; Novo Nordisk Inc.; Vivus Inc.
 
Shashank Joshi, MD, FACP, FRCP
Retained Consultant: Bayer Zydus Pharma; Franco Indian; Johnson & Johnson Services, Inc.; Marico; sanofi-aventis U.S. LLC
Speakers Bureau: Abbott Laboratories; AstraZeneca; Bayer Zydus Pharma; Boehringer Ingelheim Pharmaceuticals, Inc; Dr. Reddy Labs; Eli Lilly and Company; Glenmark; Johnson & Johnson Services, Inc.; Marico; MSD; Novartis; Novo Nordisk Inc.; Pfizer Inc.; Roche; sanofi-aventis US LLC; Zydus Cadilla;
Advisory Board: Abbott Laboratories; Boehringer Ingelheim Pharmaceuticals, Inc; Novartis; Novo Nordisk Inc.; Pfizer Inc.; Roche; USV
 
Laurence Katznelson, MD
Grant/Research Support: Novartis; Versartis, Inc
Retained Consultant: Chiasma, Inc; Pfizer Inc.; Reset Therapeutics
 
Jonathan D. Leffert, MD, FACP
Grant/Research Support: AbbVie Inc; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol Meyers Squibb; Eli Lilly and Company; Johnson & Johnson; Merck & Co., Inc; Novo Nordisk Inc; sanofi-aventis U.S. LLC
 
Matthew J. Levine, MD, FACE
Speaker’s Bureau: AbbVie Inc.
 
W. Reid Litchfield, MD
Speaker’s Bureau: Novo Nordisk Inc.
 
Mark A. Lupo, MD, FACE, ECNU
Grant/Research Support: Eisai Inc.; Patheway Genomics; Roche Diagnostics; Rosetta Genomics; Veracyte Inc.
Speakers Bureau: AbbVie Inc.; Sanofi-Genzyme; Veracyte Inc.
Advisory Board: Rosetta Genomics; Sanofi-Genzyme
 
Christos Mantzoros, MD
Grant/Research Support: Eisai Inc.; Novo Nordisk Inc.
Advisory Board: Ansh; Intarcia Therapeutics Inc.; Coherus Biosciences; Novo Nordisk Inc; Pangea
Stockholder: Coherus Biosciences; Pangea
 
Janet B. McGill, MD
Grant/Research Support: AstraZeneca/Boehringer Ingelheim Pharmaceuticals, Inc; Novartis
Retained Consultant: Aegerion; Boehringer Ingelheim Pharmaceuticals, Inc;
Dexcom, Inc.
Speakers Bureau: Aegerion; Dexcom, Inc; Janssen Pharmaceuticals Inc.; Mannkind
Advisory Board: Bayer Healthcare; Boehringer Ingelheim Pharmaceuticals, Inc; Novo Nordisk Inc.; Intarcia Therapeutics Inc.
 
Rachel Pessah-Pollack, MD
Speakers Bureau: Boehringer Ingelheim Pharmaceuticals, Inc/Eli Lilly and Company; Radius Health, Inc.
 
Cheryl R. Rosenfeld, DO
Retained Consultant: Boehringer Ingelheim Pharmaceuticals, Inc; Eisai Inc.; Novo Nordisk Inc.
Editorial Assistance (Editor): Novartis
 
Susan Samson, MD, PhD, FRCPC (Program Vice Chair)
Grant/Research Support: Novartis
Advisory Board: Chiasma, Inc; Corcept Therapeutics; Novartis
 
Lance Sloan, MD
Speakers Bureau: AstraZeneca; Boehringer Ingelheim Pharmaceuticals, Inc/Eli Lilly and Company; Janssen Pharmaceuticals Inc.; Merck & Co., Inc; Orexigen Therapeutics, Inc; Salix Pharmaceuticals Inc.
 
Dace L. Trence, MD, FACE
Stockholder: Medtronic, Inc.; sanofi-aventis U.S. LLC.
 
Aaron Vinik, MD, PhD, FCP, MACP, FACE
Retained Consultant: Alnylam Pharmaceuticals, Inc.
 
Nelson B. Watts, MD, FACP
Lecturer: Amgen Inc.; Radius Health, Inc.; Shire
Advisory Board: Amgen Inc.
Stockholder: OsteoDynamics
 
Sandra L. Weber, MD, FACP
Grant/Research Support: National Institutes of Health; Novo Nordisk Inc.; sanofi-aventis U.S., LLC
 
Kathleen Wyne, MD, PhD, FNLA
Grant/Research Support: Eli Lilly and Company; sanofi-aventis U.S. LLC
Advisory Board: AbbVie Inc.; Novo Nordisk Inc.
 
Farhad Zangeneh, MD
Retained Consultant: AbbVie Inc.; AstraZeneca; Boehringer Ingelheim Pharmaceuticals, Inc; Eli Lilly and Company; Janssen Pharmaceuticals Inc.; Novo Nordisk Inc.; Pfizer Inc.
Speakers Bureau: AbbVie Inc.; AstraZeneca; Boehringer Ingelheim Pharmaceuticals, Inc; Eli Lilly and Company; Janssen Pharmaceuticals Inc.; Novo Nordisk Inc.; Pfizer Inc.
 
Nothing to Disclose:
Vin Tangpricha, MD, PhD
Gregory Randolph, MD
Mack Harrell, MD, FACP, FACE, ECNU
Felice Caldarella, MD, FACP, CDE
Karel Pacak, MD, PhD, DSc, FACE
David Bimston, MD
Sripriya Raman, MD
Sethu K. Reddy, MD, MBA, FRCPC, FACP, MACE
Daniel L. Hurley, MD
Harmeet S. Narula, MD, FACP
David Lieb, MD
Victor Roberts, MD, MBA, FACP
Peter Singer, MD
 
*designates a member of both faculty and program committee  
 
Faculty Disclosures
Richard E. Pratley, MD (Chair)
Grant/Research Support: Eli Lilly and Company; Lexicon Pharmaceuticals, Inc.; Ligand Pharmaceuticals, Inc.; Merck & Co., Inc; Novo Nordisk Inc.; sanofi-aventis U.S. LLC; Takeda Pharmaceutical Company Ltd.
Retained Consultant: AstraZeneca; Boehringer Ingelheim Pharmaceuticals, Inc; Eisai, Inc.; Eli Lilly and Company; GlaxoSmithKline; Janssen Pharmaceuticals, Inc.; Ligand Pharmaceuticals, Inc.; Merck & Co., Inc; Novo Nordisk Inc.; Pfizer, Inc; sanofi-aventis U.S. LLC; Takeda Pharmaceutical Company Ltd.
Speakers Bureau: Novo Nordisk Inc; Takeda Pharmaceutical Company Ltd

Bruce W. Bode, MD
Grant/Research Support: Abbott Laboratories; DexCom; Diasome; Mannkind Corporation; Medtronic; Novo Nordisk Inc;
sanofi-aventis U.S. LLC; Senseonics
Retained Consultant: Adocia; Medtronic; Novo Nordisk Inc; sanofi-aventis U.S. LLC
Speakers Bureau: AstraZeneca; Eli Lilly and Company; Janssen Pharmaceuticals, Inc.; Medtronic; Novo Nordisk Inc.; sanofi-aventis U.S. LLC.
Advisory Board: Janssen Pharmaceuticals, Inc.
 
Irl B. Hirsch, MD
Retained Consultant: Abbott Laboratories; Intarcia Therapeutics, Inc.; Roche
 
Guillermo E. Umpierrez, MD
Grant/Research Support: AstraZeneca; Boehringer Ingelheim Pharmaceuticals, Inc; Merck & Co., Inc; Novo Nordisk Inc.; sanofi-aventis U.S. LLC
 
Paradigm Medical Communications, LLC, staff members have no financial relationships to disclose.
 
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA.
 
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