What to Do With What’s New in Pemphigus Vulgaris
 
Release Date: January 28, 2020
Last Reviewed: January 6, 2020
Expiration Date: January 28, 2021
Time to Complete Activity: 1.0 hour
 
Faculty
Saira Z Sheikh, MD

Assistant Professor of Medicine
Rheumatology, Allergy & Immunology
Director, UNC Rheumatology Lupus Clinic
Director, Clinical Trials Program
UNC Thurston Arthritis Research Center
University of North Carolina at Chapel Hill
Chapel Hill, NC
 
Donna A. Culton, MD, PhD
Associate Professor
Department of Dermatology
University of North Carolina at Chapel Hill
Chapel Hill, NC
 
This activity is provided by Paradigm Medical Communications, LLC. UNLV School of Dental Medicine is the educational partner.
  
       
Target Audience
This activity has been designed to address the educational needs of clinicians who diagnose and treat patients with pemphigus vulgaris (PV), including dermatologists, dentists, and rheumatologists. It may also benefit other clinicians who care for patients with PV.
 
Statement of Need
Pemphigus vulgaris belongs to a group of rare autoimmune mucocutaneous blistering disorders that were often fatal prior to the introduction of effective treatments. Management has evolved from corticosteroids to steroid-sparing immunosuppressant agents. PV is challenging to diagnose and challenging to treat, and the lack of US guidelines or comparative clinical trials leaves clinicians without clear direction for management. While dermatologists are typically the primary clinicians to diagnose and manage PV, dental clinicians are well positioned to aid in the diagnosis, since they may be the first healthcare practitioners (HCPs) to notice oral lesions that occur in PV. Other clinicians such as rheumatologists help administer some of the treatments and assist in the prevention and management of adverse treatment effects of corticosteroids. Many clinicians across all of these disciplines would benefit from continuing education (CE) that delineates evidence-based recommendations for diagnosis and management of PV, including how to integrate current and emerging clinical trial data into the decision-making process.
 
Learning Objectives
Upon proper completion of this activity, participants should be better able to:
• Diagnose PV based on presenting symptoms and appropriate testing
• Formulate evidence-based treatment strategies for patients with PV based on characteristics and comorbidities
 
Physician Accreditation Statement
Paradigm Medical Communications, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
 
Physician Credit Designation Statement
Paradigm Medical Communications, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 
Dental Professional Continuing Education
This continuing education activity has been planned and implemented in accordance with the standards of the ADA Continuing Education Recognition Program (ADA CERP) through joint efforts between UNLV School of Dental Medicine and Paradigm Medical Communications, LLC.

 
UNLV School of Dental Medicine is an ADA CERP approved provider. ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry.
 
Concerns or complaints about a CE provider may be directed to the provider or to the Commission for Continuing Education Provider Recognition at ADA.org/CERP.
 
The UNLV School of Dental Medicine designates this activity for 1.0 continuing education credits.
 
This activity has been planned and implemented in accordance with the standards of the Academy of General Dentistry Program Approval for Continuing Education (PACE) through the joint program provider approval of UNLV School of Dental Medicine and Paradigm Medical Communications, LLC.
 
UNLV School of Dental Medicine is designated as an Approved PACE Program Provider by the Academy of General Dentistry. The formal continuing education programs of this program provider are accepted by the AGD for Fellowship/Mastership and membership maintenance credit. Approval does not imply acceptance by a state or provincial board of dentistry or AGD endorsement. Nationally Approved From 6/1/2017 - 5/31/2021. Provider ID #213111
 
PA Continuing Education
PAs may claim a maximum of 1.0 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society.
 
Nurse Practitioner Continuing Education
The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.
 
This activity is supported by an educational grant from Genentech, Inc.
 
Instructions for Participation
To receive a CE certificate of participation, you should:
• Follow instructions to register or log in with your professional information and complete the pre-activity assessment
• View the online activity in its entirety.
• Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest.
 
A certificate of participation/certificate of completion will be available for download/printing immediately following your successful completion of the posttest and evaluation.
 
For questions regarding CE credit, contact the Paradigm CME Department at (845) 398-5949.
 
There is no fee required for participation in this activity.
 
Hardware/Software Requirements
This certified CME activity is designed using HTML5 web components. As you navigate the presentation using the supplied controls, the slides will sync to the speaker.
 
Supported Browsers (Desktop/Mobile)
Chrome 45+, Firefox 40+, Edge, Edge Chromium, Safari 8+, Opera 31+
 
For Tablets (iPad/Android/Surface)
iOS Safari 4 or higher, Android 2.3 or higher, IE Mobile 10 or higher
 
PDF documents
This activity may contain PDF documents. Most current browsers support viewing of PDFs natively, but you may also download a free version of Adobe Acrobat Reader here: http://get.adobe.com/reader
 
Technical Support: If you have any technical problems or playback issues email us at contactus@paradigmmc.com.
 
Disclosures
In accordance with ACCME, ADA CERP and PACE requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below.
 
Saira Z Sheikh, MD
Nothing to disclose
 
Donna A. Culton, MD, PhD
Consulting Fees: Principia Biopharma
Contracted Researcher: Principia Biopharma
Data Safety Monitoring Board: Cabaletta Bio
 
Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.
 
UNLV School of Dental Medicine staff members have no financial relationships to disclose.
 
Peer reviewer, Giuseppe Militello, MD, has the following relationships to disclose:
Investigator: AbbVie Inc
 
Resolution of Conflict of Interest
Paradigm Medical Communications, LLC and UNLV School of Dental Medicine have implemented a system to resolve conflicts of interest for each CE activity to help ensure content is objective, fair and balanced, independent, and aligned with the public interest. Conflicts, if any, are resolved through one or more processes. All CE content in this activity was independently reviewed to ensure that it is free of commercial bias, scientifically rigorous, aligned with the public interest, and compliant with all regulatory guidance and the ADA CERP Recognition Standards and Procedures, PACE Guidelines and ACCME’s Standards for Commercial Support of Continuing Medical Education.
 
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the FDA.
 
Disclaimer
This CE activity represents the views and opinions of the individual faculty, and does not constitute the opinion or endorsement of, or promotion by, Paradigm Medical Communications, LLC or UNLV School of Dental Medicine. Reasonable efforts have been taken to present educational subject matter in a balanced, unbiased fashion, and in compliance with regulatory requirements. However, each activity participant must always use his or her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.
 
If included, signed statements of informed consent granting permission for publication have been obtained for all photographs and videos in which an individual can be identified.
 
As accredited providers, Paradigm Medical Communications, LLC and UNLV School of Dental Medicine activities must include a balanced view of therapeutic options. Use of generic names contributes to this impartiality. The use of trade names should not be viewed as an endorsement of specific products by Paradigm Medical Communications, LLC or UNLV School of Dental Medicine.
 
Terms of Use and Privacy Policy
Disclaimer
The materials provided for this activity are for informational purposes only and should not be used for diagnosis or treatment of a health problem without consulting a licensed medical professional. This CE activity represents the views and opinions of the individual faculty, and does not constitute the opinion or endorsement of, or promotion by, Paradigm Medical Communications, LLC or UNLV School of Dental Medicine. References to any entity, product, service, or source of information on this website should not be considered an endorsement, either direct or implied, by Paradigm Medical Communications, LLC or UNLV School of Dental Medicine. Paradigm Medical Communications, LLC, and UNLV School of Dental Medicine accept no liability for the content referenced in this activity.
 
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The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing the program. Required items include first name, last name, degree, and email address. These items are necessary. Participants are also required to complete an evaluation of the CE activity. All evaluative information submitted is collected and retained, and used by Paradigm Medical Communications, LLC and UNLV School of Dental Medicine to continuously improve the learning experience.
 
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