Operation Diabetes: Optimizing Use of GLP-1 Receptor Agonists - Infographic Primer
Release Date: May 15, 2020
Last Reviewed: May 7, 2020
Expiration Date: May 15, 2021
Time to Complete Activity: 0.25 hour
Vivian Fonseca, MD
Professor of Medicine and Pharmacology
Tullis Tulane Alumni Chair in Diabetes
Chief, Section of Endocrinology
Tulane University Health Sciences Center
New Orleans, LA
Javier Morales, MD, FACP, FACE
Associate Clinical Professor of Medicine
Donald and Barbara Zucker School of Medicine at Hofstra Northwell
Vice President, Advanced Internal Medicine Group, PC
East Hills, NY
Debbie A. Hinnen, APN, BC-ADM, CDE, FAAN, FAADE
Advanced Practice Nurse and Certified Diabetes Educator
University of Colorado Health
Colorado Springs, CO
Adjunct Faculty, Graduate Nursing Department
Wichita State University
This activity is provided by Paradigm Medical Communications, LLC.
This activity has been designed to address the educational needs of primary care clinicians. It may also be of benefit to other healthcare professionals who manage patients with diabetes using glucagon-like peptide-1 (GLP-1) receptor agonists.
Statement of Need
The incidence of diabetes, particularly type 2 diabetes (T2D), is increasing, and with this increase comes an associated rise in diabetes complications and comorbidities such as obesity, cardiovascular disease (CVD), and renal disease. There are several classes of agents to treat hyperglycemia from which clinicians can choose. In recent years, data on GLP-1 receptor agonists have emerged demonstrating beneficial extraglycemic effects, yet the level of benefit varies among different members of the class. Most recent guideline recommendations include preferences for GLP-1 receptor agonists to individualize therapy for patients with diabetes and CVD. Despite these benefits, the uptake of and adherence to GLP-1 receptor agonist therapy is low. Because the majority of T2D management occurs in the primary care setting, primary care providers play a crucial role in optimizing T2D therapy. However, primary care providers are challenged to remain abreast of the latest data on GLP-1 receptor agonists, the clinical distinctions between class members, managing side effects, and strategies for patient education about GLP-1 receptor agonists and how to increase adherence to therapy.
Upon proper completion of this activity, participants should be better able to:
- Select treatment for patients who have diabetes based on the extraglycemic effects of GLP-1 receptor agonists
- Formulate management strategies to relieve common adverse events associated with GLP-1 receptor agonist therapy
- Outline key elements of GLP-1 receptor agonist therapy to include in patient education
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This activity is supported by an educational grant from Novo Nordisk Inc.
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In accordance with ACCME requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below.
Vivian Fonseca, MD
Consulting Fees: Abbott Laboratories; Asahi Kasea Pharma Corporation; AstraZeneca; Eli Lilly and Company; Intarcia Therapeutics; Novo Nordisk Inc.; sanofi-aventis U.S. LLC; Takeda Pharmaceutical Company
Grant/Research Support: Bayer Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals, Inc
Ownership interest: Amgen; BRAVE4Health; Insulin Algorithms; Microbiome Technologies
Javier Morales, MD, FACP, FACE
Consulting Fees: Boehringer Ingelheim Pharmaceuticals, Inc; Eli Lilly and Company; Intarcia Therapeutics; Novo Nordisk Inc.
Speakers Bureau: AstraZeneca; Boehringer Ingelheim Pharmaceuticals, Inc; Eli Lilly and Company; Novo Nordisk Inc.
Debbie A. Hinnen, APN, BC-ADM, CDE, FAAN, FAADE
Consulting Fees: Eli Lilly and Company; Janssen Pharmaceuticals; Novo Nordisk Inc.; sanofi-aventis U.S. LLC
Speakers Bureau: Eli Lilly and Company; Janssen Pharmaceuticals; Novo Nordisk Inc.; sanofi-aventis U.S. LLC
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Independent peer, resident/fellow, and patient reviewers have no financial relationships to disclose.
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