Diagnosis and Treatment of Castleman Disease: The Role of the Oncology Nurse

Release Date: November 30, 2020 
Last Reviewed: November 24, 2020
Expiration Date: November 30, 2021
Time to Complete Activity: 1.25 hours

*This activity expired for credit on November 30, 2021 and is no longer available for credit

David C. Fajgenbaum, MD, MBA, MSc

Assistant Professor of Medicine
Division of Translational Medicine and Human Genetics
University of Pennsylvania
Associate Director, Patient Impact
Penn Orphan Disease Center
Founding Director
Center for Cytokine Storm Treatment & Laboratory
Co-Founder and Executive Director
Castleman Disease Collaborative Network
Philadelphia, PA

Frits van Rhee, MD, PhD
Professor of Medicine
Clinical Director
UAMS Myeloma Center
University of Arkansas for Medical Sciences
Little Rock, AR

Colleen Erb, CRNP 
Nurse Practitioner 
Perelman Center for Advanced Medicine
Philadelphia, PA

This activity is jointly provided by Global Education Group and Paradigm Medical Communications, LLC. 

In collaboration with the Castleman Disease Collaborative Network. 

Disclosure of Commercial Support
This activity is supported by an educational grant from EUSA Pharma.

Target Audience
This activity has been designed to address the educational needs of oncology nurses, including advanced practice nurses (APNs) and registered nurses (RNs). It will also benefit other clinicians who manage patients with Castleman disease.

Learning Objectives
After completing this activity, the participant should be better able to:

  • Outline the signs and symptoms of Castleman disease as they relate to early diagnosis
  • Describe FDA-approved and guideline-recommended therapies for Castleman disease

Nursing Continuing Education
Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation.

This educational activity for 1.25 contact hours is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioner Continuing Education
This activity has been planned and implemented in accordance with the Accreditation Standards of the American Association of Nurse Practitioners (AANP) through the joint providership of Global Education Group and Paradigm Medical Communications, LLC. Global Education Group is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 110121. This activity is approved for 1.25 contact hours (which includes 0.1 hour(s) of pharmacology).

Physician Assistants Continuing Education
This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 1.25 AAPA Category 1 CME credits. Approval is valid from 11/30/2020 to 11/30/2021 . PAs should only claim credit commensurate with the extent of their participation. AAPA reference number: CME-201465.

Term of Offering
This activity was released on November 30, 2020 and is valid for one year. Requests for credit must be made no later than November 30, 2021. 

Global Contact Information
For information about the approval of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com.

Instructions for Participation 
To receive a CE certificate of participation, you should:

  • Follow instructions to register or log in with your professional information and complete the pre-activity assessment
  • View the online activity in its entirety
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest

A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.

For questions regarding claiming credit, contact the Paradigm CME Department at (845) 398-5949 or cme@paradigmmc.com.

There is no fee required for participation in this activity.

Hardware/Software Requirements
This certified CME activity is designed using HTML5 web components. As you navigate the video using the supplied controls, the slides will sync to the speaker.

Supported Browsers (Desktop/Mobile)
Chrome 45+, Firefox 40+, Edge, Edge Chromium, Safari 8+, Opera 31+

PDF documents
This activity may contain PDF documents. Most current browsers support viewing of PDFs natively, but you may also download a free version of Adobe Acrobat Reader here: http://get.adobe.com/reader

Technical Support: If you have any technical problems or playback issues email us at contactus@paradigmmc.com.

Disclosure of Conflicts of Interest
Global Education Group (Global) requires instructors, planners, managers and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by Global for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

Name of Faculty or Presenter

Reported Financial Relationship

David C. Fajgenbaum, MD, MBA, MSc

Grant/Research Support: EUSA Pharma; 
Janssen Pharmaceuticals, Inc


Frits van Rhee, MD, PhD

Consulting Fees: Adaptive Biotechnologies; EUSA Pharma; Karyopharm; Secura Bio; 
Takeda Pharmaceutical Company Ltd

Colleen Erb, CRNP 

No financial relationships to disclose


The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

Name of Planner or Manager

Reported Financial Relationship

Ashley Marostica, RN, MSN

No financial relationships to disclose

Kristin Delisi, NP

No financial relationships to disclose

Andrea Funk

No financial relationships to disclose

Liddy Knight

No financial relationships to disclose

Ashley Cann

No financial relationships to disclose

Andrea Primeau

No financial relationships to disclose

Alfred Saint Jacques

No financial relationships to disclose

Kimberly Joab

No financial relationships to disclose

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This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global and Paradigm do not recommend the use of any agent outside of the labeled indications.  

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

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