Addressing the Challenges of IBS and Chronic Idiopathic Constipation

Addressing the Challenges of IBS and Chronic Idiopathic Constipation

Release Date: July 11, 2014

Last Reviewed: June 13, 2014

Expiration Date: July 11, 2015

Time to Complete Activity: 1.0 hour

*This activity expired for credit on July 11, 2015 and is no longer available for credit

Faculty

Anthony Lembo, MD (Chair)

Associate Professor of Medicine,

Division of Gastroenterology

Harvard Medical School

Beth Israel Deaconess Medical Center

Boston, MA

Brooks D. Cash, MD, FACP, FACG

Professor of Medicine

Division of Gastroenterology

University of South Alabama

Mobile, AL

Lucinda A. Harris, MD, MS

Associate Professor of Medicine

Division of Gastroenterology and Hepatology

Mayo School of Medicine

Scottsdale, AZ

Target Audience

This activity has been designed to meet the educational needs of physicians specializing in internal medicine as either a primary or subspecialty, nurse practitioners, physician assistants, and other healthcare providers (HCPs) interested in the management of patients with IBS.

Statement of Need

Irritable bowel syndrome (IBS) and chronic idiopathic constipation (CIC) are chronic and at times debilitating conditions that exact a high physical, emotional, and financial toll on affected patients. Symptoms associated with these conditions prompt about 23 million outpatient visits to HCPs annually. In many cases, symptoms remain unresolved for years, in part because clinicians remain unfamiliar with how to accurately diagnose IBS (including subtypes) and CIC. Conventional treatments prescribed by HCPs typically target only 1 or 2 symptoms, leading to inadequate relief and patient dissatisfaction. This enduring activity will provide participants with education on guidelines for diagnosis and treatment of IBS and CIC, including how to integrate new targeted therapies into clinical practice.

Learning Objectives

Upon proper completion of this activity, participants should be better able to:

Describe evidence-based inclusion criteria for diagnosing IBS (subtypes), CIC, and opioid-induced constipation, as well as alarm symptoms that require further workup for differential diagnosis.
Appropriately incorporate new targeted therapies into treatment plans for patients with IBS (subtypes), CIC, and opioid-induced constipation based on individual patient characteristics and current clinical evidence.

Table of Contents

Incidence and Impact of Functional Gastrointestinal Disorders
IBS-C: Challenges, Myths and Realities, and Management Pearls
CIC: Challenges, Myths and Realities, and Management Pearls
Opioid-Induced Constipation: Challenges, Myths and Realities, and Management Pearls
Conclusions

Accreditation Statement

Paradigm Medical Communications, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation Statement

Paradigm Medical Communications, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physician Assistant Continuing Education

AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 1.0 hour of Category 1 credit for completing this program.

Nurse Practitioner Continuing Education

Global Education Group is approved as a provider of nurse practitioner continuing education by the American Association of Nurse Practitioners: AANP Provider Number 1101021.

This program has been approved for 1.0 contact hour of continuing education (which includes .30 hours of pharmacology).

This program was planned in accordance with AANP CE Standards and Policies and AANP Commercial Support Standard.

Disclosure of Commercial Support

This activity is supported by an educational grant from Forest Research Institute, a subsidiary of Forest Laboratories, Inc., and Ironwood Pharmaceuticals.

Instructions for Participation

To receive a CE certificate of participation, participants should:

Follow instructions to register or log in with your professional information and complete the pretest.
View the online activity in its entirety.
Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest.

A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.

There is no fee required for participation in this activity.

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Disclosure of Conflicts of Interest

Paradigm Medical Communications, LLC and Global Education Group (Global) requires instructors, planners, managers, and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by Paradigm and Global for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

*Name of Faculty or Presenter*	*Reported Financial Relationship*
Anthony Lembo, MD (Chair)	*Consultant:*Ardelyx, Inc; AstraZeneca Pharmaceuticals Company; Forest Laboratories, Inc; Ironwood Pharmaceuticals; Prometheus Laboratories Inc; Salix Pharmaceuticals, Inc.
Lucinda A. Harris, MD, MS	*Consultant:Forest Laboratories, Inc; Ironwood Pharmaceuticals; Prometheus Laboratories Inc; Salix Pharmaceuticals, Inc; Takeda Pharmaceutical Company Ltd Speaker’s Bureau:Ironwood Pharmaceuticals Contracted Research:*Alvine Pharmaceuticals, Inc; Rhythm Pharmaceuticals
Brooks D. Cash, MD, FACP, FACG	*Consultant:Forest Laboratories, Inc; Ironwood Pharmaceuticals; Prometheus Laboratories Inc; Salix Pharmaceuticals, Inc; Takeda Pharmaceutical Company Ltd Speakers Bureau*:Forest Laboratories, Inc; Ironwood Pharmaceuticals; Salix Pharmaceuticals, Inc; Takeda Pharmaceutical Company Ltd

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

*Name of Planner or Manager*	*Reported Financial Relationship*
Ashley Marostica, RN, MSN	Nothing to disclose
Amanda Glazar, PhD	Nothing to disclose

Paradigm Medical Communications, LLC staff members have no financial conflicts to disclose.

Independent peer reviewer has no financial conflicts to disclose.

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Paradigm Medical Communications, LLC and Global have implemented a system to resolve conflicts of interest for each CME activity to help ensure content objectivity, independence, fair balance, and that the content is aligned with the interest of the public. Conflicts, if any, are resolved through one or more processes. All CME content in this activity was independently reviewed to ensure that it is free of commercial bias, scientifically rigorous, aligned with the public interest, and compliant with all regulatory guidance and the ACCME’s Standards for Commercial Support of Continuing Medical Education.

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