Articulating the Role of Antiplatelet Therapy in Patients With Acute Coronary Syndromes and Prior MI Challenges, Gray Areas, and Evolving Data


Articulating the Role of Antiplatelet Therapy in Patients With Acute Coronary Syndromes and Prior MI: 
Challenges, Gray Areas, and Evolving Data


Release Date: June 30, 2020
Last Reviewed: June 20, 2020
Expiration Date: June 30, 2021
Time to Complete Activity: 2.0 Hours


Faculty
Deepak L. Bhatt, MD, MPH (Faculty Chair)

Professor of Medicine
Harvard Medical School
Executive Director of Interventional Cardiovascular Programs
Brigham and Women’s Hospital Heart and Vascular Center
Boston, MA

Dominick J. Angiolillo, MD, PhD, FACC, FESC, FSCAI
Professor of Medicine
Director, Cardiovascular Research
Program Director, Interventional Cardiology Fellowship 
University of Florida College of Medicine-Jacksonville 
Division of Cardiology
Jacksonville, FL

Christopher Cannon, MD
Education Director, Cardiovascular Innovation 
Preventive Cardiology Section, Brigham and Women’s Hospital
Professor of Medicine, Harvard Medical School
Boston, MA 

Christopher B. Granger, MD 
Professor of Medicine
Director, Cardiac Intensive Care Unit
Duke University School of Medicine
Durham, NC

Michelle L. O’Donoghue, MD, MPH
Associate Professor of Medicine
Harvard Medical School
Senior Investigator, TIMI Study Group
Associate Physician, Cardiovascular Division
Brigham and Women’s Hospital
Boston, MA

E. Magnus Ohman, MD, FRCPI, FESC, FACC, FSCAI
Professor of Medicine
The Kent and Siri Rawson Director, Duke Program for Advanced Coronary Disease
Vice-Chair, Department of Medicine—Development and Innovation
Associate Director, Duke Heart Center
Senior Investigator, Duke Clinical Research Institute
Duke University Medical Center
Durham, NC
This activity is provided by Paradigm Medical Communications, LLC.  

Target Audience
This activity has been designed to address the educational needs of clinical and interventional cardiologists, primary care physicians, nurse practitioners, and PAs. It may also benefit other clinicians who are involved in antiplatelet decision-making for patients who have acute coronary syndromes (ACS) and a history of myocardial infarction (MI).

Learning Objectives
Upon proper completion of this activity, participants should be better able to:
  • Select optimal antiplatelet treatment for heterogeneous patients with ACS and a history of MI based on current data
  • Individualize the duration of dual antiplatelet therapy (DAPT) in patients with ACS and a history of MI based on the latest evidence and unique patient characteristics
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Physician Credit Designation Statement
Paradigm Medical Communications, LLC designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

PA Continuing Education
PAs may claim a maximum of 2.0 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society.

Nurse Practitioner Continuing Education
The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.

Disclosure of Commercial Support
This activity is supported by an educational grant from AstraZeneca Pharmaceuticals LP. 

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Disclosures
In accordance with ACCME requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below.

Deepak L. Bhatt, MD, MPH
Grant/Research Support: Abbott Laboratories; Afimmune Ltd; Amarin Corporation; Amgen Inc.; AstraZeneca Pharmaceuticals LP; Bayer Corporation; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; Cardax, Inc.; Chiesi USA; CLS Behring; Eisai Inc.; Eli Lilly and Company; Ethicon, Inc.; Ferring Pharmaceuticals Inc.; Forest Laboratories; Fractyl Laboratories Inc.; Indorsia Ltd; Ironwood Pharmaceuticals; Ischemix Inc.; Lexicon Pharmaceuticals, Inc.; Medtronic Inc.; Pfizer Inc.; PhaseBio Pharmaceuticals, Inc.; PLx Pharma Inc.; Regeneron Pharmaceuticals, Inc.; Roche Pharma; Sanofi US; Synaptic Pharmaceuticals Corp.; The Medicines Company

Dominick J. Angiolillo, MD, PhD, FACC, FESC, FSCAI
Consulting Fees: Amgen Inc.; Aralez Pharmaceuticals Inc.; AstraZeneca Pharmaceuticals LP; Bayer Corporation; Biosensors International Ltd; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; Chiesi USA; Daiichi-Sankyo, Inc.; Eli Lilly and Company; Haemonetics Corporation; Janssen Pharmaceuticals; Merck & Co., Inc.; PhaseBio Pharmaceuticals, Inc.; PLx Pharma Inc.; Pfizer Inc.; Sanofi US; The Medicines Company
Grant/Research Support: Amgen Inc.; AstraZeneca Pharmaceuticals LP; Bayer Corporation; Biosensors International Ltd; CeloNova BioSciences, Inc.; CSL Behring; Daiichi Sankyo, Inc.; Eisai Inc.; Eli Lilly and Company; Gilead Sciences, Inc.; Idorsia Ltd; Janssen Pharmaceuticals; Matsutani Chemical Industry Co., Inc.; Merck & Co., Inc.; Novartis Pharmaceuticals; Osprey Medical, Inc.; RenalGuard Solutions, Inc.
Other: CeloNova BioSciences, Inc.; St. Jude’s Medical, Inc.


Christopher Cannon, MD
Consulting Fees: Aegerion Pharmaceuticals, Inc.; Alnylam Pharmaceuticals; Amarin Corportion; Amgen Inc.; Applied Therapeutics, Inc.; Asecndia Pharmaceuticals; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; Corvidia Therapeutics; HLS Therapeutics, Inc.; Innovent Biologics, Inc.; Janssen Pharmaceuticals; Kowa Pharmaceuticals America, Inc.; Merck & Co., Inc.; Pfizer Inc.; Sanofi US
Grant/Research Support: Amgen Inc.; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; Daiichi-Sankyo, Inc.; Janssen Pharmaceuticals; Merck & Co., Inc.; Pfizer Inc.


Christopher B. Granger, MD 
Consulting Fees: AbbVie Inc.; Bayer Corporation; Boston Scientific Corporation; Espero Biopharma; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; CeleCor Therapeutics; Correvio Pharma Corp; Janssen Pharmaceuticals; Medscape; Medtronic Inc.; Merck & Co., Inc.; Novo Nordisk Inc.; Pfizer Inc.; Rhoshan Pharmaceuticals, Inc.; Roche Diagnostics 
Grant/Research Support: Akros Pharma Inc.; Apple; AstraZeneca Pharmaceuticals LP; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; Daiichi Sankyo, Inc.; Duke Clinical Research; GlaxoSmithKline plc; Janssen Pharmaceuticals; Medtronic Foundation; Novartis Pharmaceuticals; Pfizer Inc.


Michelle L. O’Donoghue, MD, MPH
Salary/Honoraria: Medscape Cardiology
Grant/Research Support: Amgen Inc.; AstraZeneca Pharmaceuticals LP; The Medicines Company
Consulting Fees: Amgen Inc.; AstraZeneca Pharmaceuticals LP; CRICO; Janssen Pharmaceuticals; Novartis Pharmaceuticals


E. Magnus Ohman, MD, FRCPI, FESC, FACC, FSCAI
No financial relationships to disclose.

Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.

Independent peer reviewer has no financial relationships to disclose.

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