The Many Faces of Neovascular Retinal Disease: Individualizing the Use of Sustained Delivery Therapy
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Release Date: November 14, 2025
Expiration Date: November 14, 2026
Time to Complete Activity: 1.0 hour
Faculty
David A. Eichenbaum, MD, FASRS
Director of Research
Retina Vitreous Associates of Florida
Collaborative Associate Professor
Morsani College of Medicine
University of South Florida
St. Petersburg, FL
Carl D. Regillo, MD, FACS
Director, Retina Service
Wills Eye Hospital
Partner, Mid Atlantic Retina
Professor of Ophthalmology
Thomas Jefferson University
Philadelphia, PA
Target Audience
This activity has been designed to meet the educational needs of retina specialists and other ophthalmologists. It may also benefit other clinicians who are involved in the care of patients with neovascular retinal disease.
Educational Provider
This activity is provided by Paradigm Medical Communications, LLC. 
Supporter Acknowledgment
This activity is supported by an educational grant from Genentech, a member of the Roche Group.
Program Overview
Join us for a dynamic CME activity exploring the future of retinal disease management. Discover how the ranibizumab port delivery system (PDS) and other therapies—such as tyrosine kinase inhibitors and gene therapies—are transforming treatment options and patient outcomes. Learn to identify ideal candidates, navigate updated drug indications, and optimize monitoring strategies. Through a fast-paced lightning round format, this program equips retina specialists and ophthalmologists with practical insights to confidently integrate innovative therapies into clinical practice. Don’t miss this opportunity to stay ahead in retinal care and improve patient satisfaction.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Identify data that help inform the appropriate use of sustained delivery therapy in clinical practice
- Differentiate good versus poor candidates for available sustained delivery therapy
- Determine best steps to ensure optimal ongoing device safety and efficacy following PDS implantation
Physician Accreditation Statement
Paradigm Medical Communications, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Physician Credit Designation Statement
Paradigm Medical Communications, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
PA Continuing Education
PAs may claim a maximum of 1.0 Category 1 credit for completing this activity. NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society.
Nurse Practitioner Continuing Education
The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.
Hardware/Software Requirements
This accredited CME activity is designed using HTML5 web components. As you navigate the video using the supplied controls, the slides will sync to the speaker.
Supported Browsers (Desktop/Mobile)
Chrome 45+, Firefox 40+, Edge, Edge Chromium, Safari 8+, Opera 31+
PDF documents
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Instructions for Participation
To receive a certificate and claim credit, participants must:
- Follow instructions to register or log in with your professional information and complete the pretest
- View the online activity in its entirety
- Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest
A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.
For questions regarding CME credit, contact the Paradigm CME Department at cme@paradigmmc.com.
There are no fees for participating in this activity.
Disclosure of Relevant Financial Relationships
In accordance with the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education, Paradigm requires that all planners, faculty, and others who are in a position to control the content of this activity disclose all financial relationships with ineligible companies during the past 24 months.
All relevant relationships are identified and mitigated according to Paradigm policy prior to individuals assuming their roles and are disclosed prior to learners’ engagement in the activity. Paradigm is committed to providing learners with high-quality accredited continuing education that promotes improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.
The content of this activity was independently reviewed to ensure that it is fair and balanced, scientifically rigorous, evidence based, and aligned with the public interest. All relevant relationships have been mitigated.
David A. Eichenbaum, MD, FASRS
Consultant: 4D Molecular Therapeutics; AAVantegarde; AbbVie Inc.; Adverum Biotechnologies, Inc; Akari Therapeutics; Alexion Pharmaceuticals, Inc; Amaros, Inc.; ANI Pharmaceuticals, Inc.; Annexon, Inc; Apellis Pharmaceuticals, Inc; Astellas Pharma US, Inc; Bausch & Lomb; Bayer Corporation; Bitfount Ltd; Boehringer Ingelheim International GmbH; Complement Therapeutics GmbH; EcoR1 Capital, LLC; EyePoint Pharmaceuticals, Inc; Genentech, Inc.; Harrow, Inc; Imvionix; Kriya Therapeutics; Kodiak Sciences Inc; Lexitas; Nanoscope Therapeutics, Inc; Neurotech Pharmaceuticals, Inc; Notal Vision, Inc; Novartis AG; Ocugen, Inc; Ocular Therapeutix, Inc; Ocuphire Pharma, Inc (expired 2024); Ollin Biosciences; Opthea; Orasis Pharmaceuticals, Ltd; Outlook Therapeutics, Inc (expired 2024); Regeneron Pharmaceuticals Inc; REGENXBIO Inc; RetinAl Medical AG; Revive Therapeutics Ltd.; Roche Holding AG; Samsara Therapeutics; Stealth BioTherapeutics Inc; Stroke Therapeutics; Tilak Healthcare; Thermo Fisher Scientific Inc.; UNITY Biotechnology
Speakers’ Bureau: Apellis Pharmaceuticals, Inc; Astellas Pharma US, Inc; Bayer Corporation; Genentech, Inc.; Regeneron Pharmaceuticals Inc
Investigator: 4D Molecular Therapeutics; AbbVie Inc.; Adverum Biotechnologies, Inc; Alcon; Alexion Pharmaceuticals, Inc; Allgenesis Biotherapeutics Inc; Amaros, Inc.; Annexon, Inc; Astellas Pharma US, Inc; Aviceda Therapeutics; Bayer Corporation; Boehringer Ingelheim International GmbH; EyeBio; EyePoint Pharmaceuticals, Inc; Gemini Therapeutics (expired 2024); Genentech, Inc.; Gyroscope Therapeutics Limited; Ionis Pharmaceuticals; Janssen Pharmaceuticals, Inc; Kodiak Sciences Inc; Kyowa Kirin Co, Ltd; Novartis AG; Ocular Therapeutix, Inc; Oculis; OcuTerra Therapeutics (expired 2024); Ollin Biosciences; ONL Therapeutics; Opthea; Priovant Therapeutics; Regeneron Pharmaceuticals Inc; REGENXBIO Inc; RetinAl Medical AG; Roche Holding AG; Skyline Therapeutics; Stealth BioTherapeutics Inc; UNITY Biotechnology
Stocks: 4D Molecular Therapeutics; Amaros, Inc.; Boston Image Reading Center LLC; EyePoint Pharmaceuticals, Inc; Genentech, Inc.; Hemera Biosciences; Janssen Pharmaceuticals, Inc; Ollin Biosciences; Revive Therapeutics Ltd.; USRetina
Carl D. Regillo, MD, FACS
Consultant: 4D Molecular Therapeutics; Adverum Biotechnologies, Inc; Alcon; agtc; Allergan, Inc.; Amgen Inc; Annexon, Inc; Apellis Pharmaceuticals, Inc; Aviceda Therapeutics; Bausch & Lomb; BioCryst Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH; Breye Therapeutics ApS; Clearside Biomedical; Chengdu Kanghong Pharmaceutical Group Co, LTD; Cognition Therapeutics; Endogena Therapeutics Inc; EyePoint Pharmaceuticals, Inc; Genentech, Inc; IVERIC bio, Inc; Janssen Pharmaceuticals, Inc; jCyte, Inc.; Kodiac Sciences Inc; Kyoto Drug Discovery & Development Co., Ltd.; Lineage Cell Therapeutics, Inc; Merck & Co, Inc; Nanoscope Therapeutics, Inc; Neurotech Pharmaceuticals, Inc; NGM Biopharmaceuticals; Novelty Nobility Inc.; Novartis AG; Ocugen, Inc.; Oculis (expired 12/24); Ocuphire Pharma, Inc; OcuTerra Therapeutics (expired 12/24); ONL Therapeutics, Inc.; Opthea; Ora, Inc.; Orasis Pharmaceuticals (expired 12/24); Outlook Therapeutics, Inc; Ray Therapeutics; REGENXBIO Inc; Sanofi; Stealth BioTherapeutics Inc; Thea Pharma Inc; Viatris Inc.; ZEISS International; ZipBio
Research Funding: Gyroscope (expired 12/24); Iveric (expired 12/24); Notal Vision (expired 12/24)
Independent Contractor: 4D Molecular Therapeutics; Adverum Biotechnologies, Inc; agtc; Alcon; Allergan, Inc.; Annexon, Inc; Apellis Pharmaceuticals, Inc; Astellas Pharma US, Inc; EyeBio; EyePoint Pharmaceuticals, Inc; Genentech, Inc; Gyroscope Therapeutics Limited (expired 12/24); IVERIC bio, Inc (expired 12/24); Janssen Pharmaceuticals, Inc; Kodiac Sciences Inc; Lineage Cell Therapeutics, Inc; NGM Biopharmaceuticals; Notal Vision, Inc (expired 12/24); Novartis AG; Ocugen, Inc; OcuTerra Therapeutics; Opthea; Regeneron Pharmaceuticals Inc; REGENXBIO Inc; Stealth BioTherapeutics Inc
Stocks: Aviceda Therapeutics; Ocugen, Inc.; ZipBio
Paradigm Medical Communications, LLC staff members have no relevant financial relationships with ineligible companies to disclose.
Peer Reviewer
Stock: CytomX Therapeutics Inc (expired 1/25); F. Hoffmann-La Roche Ltd (expired 3/24); Medtronic (expired 3/24); Pfizer Inc. (expired 3/24)
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the FDA.
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