GET-REAL: Guide to Evaluation and Treatment of Venous Thromboembolism Using REAL-World Data

Release Date: January 29, 2021 
Last Reviewed: January 27, 2021
Expiration Date: January 29, 2022
Time to Complete Activity: 1.0 hour

*This activity expired for credit on January 29, 2022 and is no longer available for credit

Gregory Piazza, MD, MS

Director, Vascular Medicine Section
Division of Cardiovascular Medicine
Brigham and Women’s Hospital
Associate Professor of Medicine
Harvard Medical School
Boston, MA

Joshua A. Beckman, MD, MS
Professor of Medicine
Director, Vascular Medicine
Vanderbilt University Medical Center
Nashville, TN
This activity is provided by Paradigm Medical Communications, LLC.  

Disclosure of Commercial Support
This activity is supported by an educational grant from the Bristol-Myers Squibb and Pfizer Alliance.    

Target Audience
This activity has been designed to address the educational needs of venous thromboembolism (VTE) specialists, pulmonologists, hematologist/oncologists, vascular surgeons, emergency department physicians, internists, family medicine practitioners, allied healthcare professionals (HCPs), and other clinicians who are involved or interested in the management of patients with VTE.

Statement of Need
VTE is a common and potentially deadly vascular disease associated with a high rate of recurrence. Therefore, long-term anticoagulation treatment is often needed to prevent future events. Although randomized controlled trials (RCTs) have been instrumental in informing a shift toward preferential use of direct oral anticoagulants (DOACs) versus warfarin or low-molecular-weight heparin (LMWH) in many patients with VTE, the shortcomings of these trials (eg, lack of head-to-head comparisons and limitations in the number and type of patients studied) leave clinicians with little guidance on optimal treatment of the diverse patient subsets they encounter. Real-world evidence (RWE) studies can be instrumental in filling this void. This interactive DASHboard webinar will provide an overview of the methodology, quality, and key findings from recent RWE studies on this topic, along with case studies, to help the wide variety of clinicians involved in the care of patients with VTE interpret and apply these data to ensure safe, effective, and individualized treatment.

Learning Objectives
Upon completion of this activity, participants should be able to:

  • Evaluate the benefits and limitations of high-quality RWE studies in the context of anticoagulation decision-making for patients with VTE 
  • Select evidence-based treatment plans for VTE that demonstrate understanding of the real-world benefits and risks of DOACs, warfarin, and LMWH across a variety of patient types 


  • Assessment and Value of RWE
  • VTE Management: Deciphering RWE, RCTs, and Guideline Recommendations
  • Case Studies: Applying RWE to Clinical Practice 

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  • View the online activity in its entirety
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest

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In accordance with ACCME requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below. Any potential conflicts of interest have been resolved.

Gregory Piazza, MD, MS
Salary: Boston Scientific Corporation (spouse)
Consulting Fees: Agile Therapeutics; Amgen Inc
Grant/Research Support: Bayer HealthCare; Boston Scientific; Bristol-Myers Squibb Company and Pfizer Alliance; Janssen Pharmaceuticals, Inc; Portola Pharmaceuticals, Inc

Joshua A. Beckman, MD 
Consulting fees: Amgen Inc; Bayer Corporation; Janssen Pharmaceuticals, Inc; JanOne
Grant/Research support: Novartis
Stockholder: EMX Royalty Corp; Jana Care Inc. 

Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.

Independent peer reviewer has no financial relationships to disclose. 

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