Discovering New Targets and Unique Strategies to Treat Sjögren’s Disease



Release Date: November 25, 2025
Expiration Date: November 25, 2026
Time to Complete Activity: 0.5 hour

Faculty

Thomas Grader-Beck, MD
Associate Professor of Clinical Medicine
Division of Rheumatology 
Johns Hopkins School of Medicine 
Baltimore, MD

Ghaith Noaiseh, MD
Associate Professor of Medicine
Director, Sjogren’s Center
University of Kansas Health System
Division of Allergy, Clinical Immunology, and Rheumatology
Department of Medicine
The University of Kansas Health System  
Kansas City, KS

 

Target Audience 

This activity has been designed to meet the educational needs of rheumatology clinicians (including physicians, nurse practitioners, and PAs) and pharmacists.
 

Educational Provider 

This activity is jointly provided by Paradigm Medical Communications, LLC and Educational Review Systems, Inc. 
 

In collaboration with the Sjögren’s Foundation. 


 

Supporter Acknowledgment 

This activity is supported by an educational grant from Novartis.    
 

Program Overview 

This interactive infographic will focus on the pathophysiology of Sjögren’s disease (SjD), supporting the rationale for the mechanisms of action of emerging targeted B-cell treatments in SjD and clinical data. This will include discussions of trial designs and outcomes measured, including impact on quality of life. The faculty discussions will reflect on treatment targets and highlight potential clinical applications of emerging agents.
 

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Outline the rationale behind targets of emerging agents to treat SjD
  • Assess clinical data for emerging agents in SjD
  • Evaluate potential clinical applications of emerging agents for patients with SjD based on clinical data

 

Physician Accreditation Statement    

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Paradigm Medical Communications, LLC and Educational Review Systems, Inc. Paradigm Medical Communications, LLC is accredited by the ACCME to provide continuing medical education for physicians.
 

Physician Credit Designation Statement

Paradigm Medical Communications, LLC designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 
 

PA Continuing Education 

PAs may claim a maximum of 0.5 Category 1 credit for completing this activity. NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society.
 

Nurse Practitioner Continuing Education 

The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.
 

Pharmacist Accreditation and Designation Statement

Educational Review Systems is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. Participants of the session who complete the evaluation and provide accurate NABP e-Profile information will have their credit for 0.5 contact hours (0.05 CEU) submitted to CPE Monitor as early as 14 days after the event and no later than 60 days after the event.  Please know that if accurate e-Profile information is not provided within 60 days of the event, credit cannot be claimed after that time.  The participant is accountable for verifying the accurate posting of CE credit to their CPE Monitor account within 60 days.

UAN # 0761-9999-25-223-H01-P

This is a knowledge-based activity.

 

Hardware/Software Requirements

This accredited CME activity is designed using HTML5 web components. As you navigate the video using the supplied controls, the slides will sync to the speaker.

Supported Browsers (Desktop/Mobile)
Chrome 45+, Firefox 40+, Edge, Edge Chromium, Safari 8+, Opera 31+

PDF documents
This activity may contain PDF documents. Most current browsers support viewing of PDFs natively, but you may also download a free version of Adobe Acrobat Reader here: http://get.adobe.com/reader

Technical Support: If you have any technical problems or playback issues, email us at contactus@paradigmmc.com.

Instructions for Participation
To receive a certificate and claim credit, participants must:

  • Follow instructions to register or log in with your professional information and complete the pretest
  • View the online activity in its entirety
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest

A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.

For questions regarding CME credit, contact the Paradigm CME Department at cme@paradigmmc.com.

There are no fees for participating in this activity.

 

Disclosure of Relevant Financial Relationships

In accordance with the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education, Paradigm requires that all planners, faculty, and others who are in a position to control the content of this activity disclose all financial relationships with ineligible companies during the past 24 months.

All relevant relationships are identified and mitigated according to Paradigm policy prior to individuals assuming their roles and are disclosed prior to learners’ engagement in the activity. Paradigm is committed to providing learners with high-quality accredited continuing education that promotes improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company. 

The content of this activity was independently reviewed to ensure that it is fair and balanced, scientifically rigorous, evidence based, and aligned with the public interest. All relevant relationships have been mitigated. 

Thomas Grader-Beck, MD
Advisor: Novartis AG
Consultant: Novartis AG

Ghaith Noaiseh, MD
Advisor: Amgen Inc; argenx; Janssen Pharmaceuticals, Inc; Novartis AG
Research Funding: Amgen Inc; Bristol-Myers Squibb Company; Horizon Therapeutics plc; Janssen Pharmaceuticals, Inc; Novartis AG; Sanofi

Paradigm Medical Communications, LLC, Educational Review Systems, Inc., and Sjogren's Foundation staff members have no relevant financial relationships with ineligible companies to disclose.

Independent peer reviewer has no relevant financial relationships with ineligible companies to disclose.

 

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the FDA.

Disclaimer

This CME activity represents the views and opinions of the individual faculty, and does not constitute the opinion or endorsement of, or promotion by, Paradigm Medical Communications, LLC. Reasonable efforts have been taken to present educational subject matter in a balanced, unbiased fashion, and in compliance with regulatory requirements. However, each activity participant must always use his or her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.

If included, signed statements of informed consent granting permission for publication have been obtained for all photographs and videos in which an individual can be identified.

As an ACCME-accredited provider, Paradigm Medical Communications, LLC must ensure that its activities include a balanced view of therapeutic options. Use of generic names contributes to this impartiality. The use of trade names should not be viewed as an endorsement of specific products by Paradigm Medical Communications, LLC. 

Terms of Use and Privacy Policy
Disclaimer
The materials provided for this activity are for informational purposes only and should not be used for diagnosis or treatment of a health problem without consulting a licensed medical professional. This CME activity represents the views and opinions of the individual faculty, and does not constitute the opinion or endorsement of, or promotion by, Paradigm Medical Communications, LLC. References to any entity, product, service, or source of information on this website should not be considered an endorsement, either direct or implied, by Paradigm Medical Communications, LLC. Paradigm Medical Communications, LLC accepts no liability for the content referenced in this activity.

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Collection and use of your personal information
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing the program and may be used to track registration and participation. Required items include first name, last name, degree, and email address. These items are necessary. Participants are also required to complete an evaluation of the CME activity. All evaluative information submitted is collected and retained, and used by Paradigm Medical Communications, LLC to continuously improve the learning experience.

Paradigm Medical Communications, LLC does not otherwise transfer, sell, or share personal information with outside parties. Paradigm Medical Communications, LLC will not otherwise disclose personal information unless required to in a legal process. Paradigm Medical Communications, LLC staff members review individual test results to the extent necessary to record and track participants’ credits.

 

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