The Role of the Oncology Nurse in the Diagnosis and Treatment of Castleman Disease

Release Date: November 30, 2021
Expiration Date: November 30, 2022
Time to Complete Activity:  1.0 hour

*This activity expired for credit on November 30, 2022 and is no longer available for credit


David C. Fajgenbaum, MD, MBA, MSc 

Assistant Professor of Medicine
Division of Translational Medicine and Human Genetics
Associate Director, Patient Impact
Penn Orphan Disease Center
Founding Director
Center for Cytokine Storm Treatment and Laboratory
University of Pennsylvania
Co-Founder and Executive Director
Castleman Disease Collaborative Network
Philadelphia, PA

Sudipto Mukherjee, MD, PhD, MPH                       
Director of Rare Cancers and Blood Diseases 
Department of Hematology and Medical Oncology
Leukemia Program
Taussig Cancer Institute
Cleveland Clinic
Cleveland, OH

Gretchen A. McNally, PhD, ANP-BC, AOCNP 
Nurse Practitioner—Hematology
The Ohio State University
Arthur G. James Cancer Hospital
Columbus, OH

This activity is jointly provided by Global Education Group and Paradigm Medical Communications, LLC.   
In collaboration with the Castleman Disease Collaborative Network 

This activity is supported by an educational grant from EUSA Pharma (US) LLC.    

Target Audience
This activity has been designed to address the educational needs of oncology nurses, including advanced practice nurses and registered nurses. It will also benefit PAs and other clinicians who manage patients with Castleman disease. 

Program Overview
Castleman disease (CD) is a rare group of heterogeneous lymphoproliferative disorders, many of which have an unknown underlying etiology. Owing to its rarity and unknown etiology, many oncology nurses are unaware of this disease, despite it often being managed by hematology/oncology clinics. As a result, this webinar aims to educate oncology nurses on CD so they, in turn, are equipped to educate, advocate for, and support patients through the diagnosis and treatment process.

Learning Objectives
After completing this activity, the participant should be better able to:

  • Outline the signs and symptoms of CD as they relate to early diagnosis
  • Describe US Food and Drug Administration-approved and guideline-recommended therapies for CD


  • Introduction to Castleman Disease
  • Diagnosis of Castleman Disease
  • Treatment of Castleman Disease
  • Conclusions and Faculty Discussion

Nursing Continuing Education
Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

This educational activity for 1 contact hour is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Practitioner Continuing Education
This activity has been planned and implemented in
accordance with the Accreditation Standards of the American Association of Nurse Practitioners (AANP) through the joint providership of Global Education Group and Paradigm Medical Communication, LLC. Global Education Group is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 110121. This activity is approved for 1.0 contact hour(s) (which includes 0.2 hour(s) of pharmacology).

Physician Assistants
This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 1 AAPA Category 1 CME credits. Approval is valid from 12/03/2021 to 11/30/2022. PAs should only claim credit commensurate with the extent of their participation. AAPA reference number: CME-204142.

Term of Offering
This activity was released on November 30, 2021, and is valid for one year. Requests for credit must be made no later than November 30, 2022.

Global Contact Information
For information about the accreditation of this program, please contact Global at 303-395-1782 or

Instructions for Participation 
In order to receive credit for this activity, the participant must:

  • Follow instructions to register or log in with your professional information and complete the preactivity assessment
  • View the online activity in its entirety
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest

A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.

Fee Information
There is no fee required for participation in this activity.

Hardware/Software Requirements
This certified CME activity is designed using HTML5 web components. As you navigate the video using the supplied controls, the slides will sync to the speaker.

Supported Browsers (Desktop/Mobile)
Chrome 45+, Firefox 40+, Edge, Edge Chromium, Safari 8+, Opera 31+

PDF documents
This activity may contain PDF documents. Most current browsers support viewing of PDFs natively, but you may also download a free version of Adobe Acrobat Reader here:

Technical Support: If you have any technical problems or playback issues, email us at

Disclosure of Conflicts of Interest
Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.  

All relevant financial relationships have been mitigated. 

The faculty have the following relevant financial relationships with ineligible companies:

Name of faculty or Presenter Reported Financial Relationship

David Fajgenbaum, MD, MBA, MSc                                                                                                                                                          
Grant Research Support: EUSA Pharma

Sudipto Mukherjee, MD, PhD, MPH                                                                                                                                                                                                                                                                                                   

Consultant/Independent Contractor: BioPharm International; Bristol-Myers Squibb Company; Celgene Corporation; Novartis
Grant Research Support: Bristol-Myers Squibb Company; Jazz Pharmaceuticals, Inc; Novartis
Honoraria: Bristol-Myers Squibb Company; Novartis
Speakers Bureau: EUSA Pharma; Novartis
Other: Abbvie Inc; Blueprint Medicines Corporation; Bristol-Myers Squibb Company; Celgene Corporation; EUSA Pharma; Genentech, Inc.; Novartis

Gretchen A. McNally, PhD, ANP-BC, AOCNP                                                                                                                                                                                                                                                                                                                                                                                                                                                        
Nothing to disclose

The planners and managers have the following relevant financial relationships with ineligible companies:

Name of Planner or Manager
Reported Financial Relationship                        
Rhys Williams, MSN, FNP-C, RN Nothing to disclose
Kristin Delisi, NP Nothing to disclose
Lindsay Borvansky Nothing to disclose
Andrea Funk Nothing to disclose
Liddy Knight Nothing to disclose
Ashley Cann Nothing to disclose
Kim Rodriguez Nothing to disclose
Paradigm Medical Communications, LLC staff members  Nothing to disclose

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Paradigm Medical Communications, LLC do not recommend the use of any agent outside of the labeled indications.  

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

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Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

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