Breakthroughs in Understanding and Treating Chronic Idiopathic Constipation and Irritable Bowel Syndrome
Release Date: January 29, 2015
Last Reviewed: January 8, 2015
Expiration Date: January 28, 2016
Time to Complete Activity:  1.0 hour

*This activity expired for credit on January 28, 2016 and is no longer available for credit
Brian E. Lacy, MD, PhD, FACG (Chair)
Professor of Medicine
Geisel School of Medicine at Dartmouth
Hanover, NH
Chief, Section of Gastroenterology and Hepatology
Dartmouth-Hitchcock Medical Center
Lebanon, NH
Professor of Medicine
Division of Gastroenterology
University of South Alabama
Mobile, AL
Amy E. Foxx-Orenstein, DO, FACP, FACG
Professor of Medicine
Mayo Clinic College of Medicine
Division of Gastroenterology and Hepatology
Department of Medicine
Mayo Clinic
Scottsdale, AZ
Charlene M. Prather, MD, MPH, AGAF, FACP
Professor of Internal Medicine
Director, Gastroenterology Subspecialty Residency Program
Division of Gastroenterology and Hepatology
Saint Louis University School of Medicine
St. Louis, MO
Target Audience
This activity has been designed to address the educational needs of experts in the area of gastroenterology, internists and other primary care physicians, and other allied healthcare professionals (HCPs) interested in and actively engaged in the management of patients with CIC and IBS.
Learning Objectives
Upon proper completion of this activity, participants should be better able to:
  • Describe the different pathophysiologic pathways implicated in the development of chronic idiopathic constipation (CIC) and irritable bowel syndrome (IBS).
  • Discuss current evidence-based approaches to accurately characterize CIC and IBS and differentiate them from each other and from other medical conditions that present with similar symptoms.
  • Formulate evidence-based treatment plans for patients with CIC and IBS based on ongoing assessment of symptomatology.
Accreditation Statement
Paradigm Medical Communications, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
Credit Designation Statement
Paradigm Medical Communications, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosure of Commercial Support
This activity is supported by an educational grant from Forest Research Institute, a subsidiary of Forest Laboratories, Inc., and Ironwood Pharmaceuticals.
Instructions for Participation
To receive a CME certificate of participation, participants should:
  • Follow instructions to register or log in with your professional information and complete the pre-activity assessment.
  • View the online activity in its entirety.
  • Complete and submit the online posttest and evaluation. You must answer 70% of the posttest questions correctly to earn credit. You will have unlimited opportunities to successfully complete the posttest.
A certificate of participation will be available for download/printing immediately following your successful completion of the posttest and evaluation.
There is no fee required for participation in this activity.

Hardware/Software Requirements
This certified CME activity is designed to be viewed on desktops, laptops, and tablets.
Supported Browsers
For Desktops/Laptops (Windows/Mac)
Internet Explorer 9 or higher, Firefox 28 or higher, Safari 5.1 or higher, Google Chrome 31 or higher, Opera 21 or higher
For Tablets (iPad/Android/Surface)
iOS Safari 4 or higher, Android 2.3 or higher, IE Mobile 10 or higher
Technical Support
If you have any technical problems or playback issues, please click on the Technical Support button on the left of the screen or email us at
In accordance with Accreditation Council for Continuing Medical Education requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below.
Brian E. Lacy, MD, PhD, FACG (Chair)
Consultant: Forest Laboratories, Inc.; Ironwood Pharmaceuticals; Salix Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Ltd
Consultant: Forest Laboratories, Inc; Ironwood Pharmaceuticals; Prometheus Laboratories Inc; Salix Pharmaceuticals, Inc; Takeda Pharmaceutical Company Ltd
Speakers Bureau: Forest Laboratories, Inc; Ironwood Pharmaceuticals; Salix Pharmaceuticals, Inc; Takeda Pharmaceutical Company Ltd
Amy E. Foxx-Orenstein, DO, FACP, FACG
Funding: Salix Pharmaceuticals; Vibrant Ltd
Consultant: Actavis; Forest Laboratories, Inc.; Ironwood Pharmaceuticals
Charlene M. Prather, MD, MPH, AGAF, FACP
No financial relationships to disclose
Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.
Independent peer reviewer has no financial relationships to disclose.
Resolution of Conflict of Interest
Paradigm Medical Communications, LLC has implemented a system to resolve conflicts of interest for each CME activity to help ensure content objectivity, independence, fair balance, and that the content is aligned with the interest of the public. Conflicts, if any, are resolved through one or more processes. All CME content in this activity was independently reviewed to ensure that it is free of commercial bias, scientifically rigorous, aligned with the public interest, and compliant with all regulatory guidance and the ACCME’s Standards for Commercial Support of Continuing Medical Education.
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA.
This CME activity represents the views and opinions of the individual faculty, and does not constitute the opinion or endorsement of, or promotion by, Paradigm Medical Communications, LLC. Reasonable efforts have been taken to present educational subject matter in a balanced, unbiased fashion, and in compliance with regulatory requirements. However, each activity participant must always use his or her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.
Terms of Use and Privacy Policy
The materials provided for this activity are for informational purposes only, and should not be used for diagnosis or treatment of a health problem without consulting a licensed medical professional. Any views or opinions presented are solely those of the Faculty, and do not necessarily represent those of Paradigm Medical Communications, LLC. References to any entity, product, service, or source of information on this website should not be considered an endorsement, either direct or implied, by Paradigm Medical Communications, LLC. Paradigm Medical Communications, LLC accepts no liability for the content referenced in this activity.
Privacy policy
Paradigm Medical Communications, LLC is committed to protecting the privacy of those who participate in the activities (herein referred to as "website") located at The information below describes the security of the website for safeguarding personal information and the rationale for collection and use of personal information.
Security/safeguarding personal information
This website has physical and procedural safeguards in place to prevent unauthorized access to personal information used to access this website.
Collection and use of your personal information
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing the program. Required items include first name, last name, degree, and email address. These items are necessary. Participants are also required to complete an evaluation of the CME activity. All evaluative information submitted is collected and retained, and used by Paradigm Medical Communications, LLC to continuously improve the learning experience.
Paradigm Medical Communications, LLC does not transfer, sell, or share personal information with outside parties. Paradigm Medical Communications, LLC will not otherwise disclose personal information unless required to in a legal process. Paradigm Medical Communications, LLC staff members review individual test results to the extent necessary to record and track participants’ credits.
Contact Us
If you have any questions or comments, please email us at
©2015 Paradigm Medical Communications, LLC, except where noted. Content may not be reproduced in whole or part without the express written permission of Paradigm Medical Communications, LLC.